B cell receptor signatures associated with strong and poor SARS-CoV-2 vaccine responses강력하고 불량한 SARS-CoV-2 백신 반응과 관련된 B 세포 수용체 신호Article Published on 2022-12-012022-09-12 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 진단, [키워드] age antibody Antibody Response B cell B cell receptor Biomarker class switch recombination clone Cohort COVID-19 healthy IgG IgM Immunity inactivated Inactivated vaccine inactivated vaccine. individuals Infection molecular mRNA Neutralizing antibodies receptor recipient Reinfection response SARS-CoV-2 SARS-CoV-2 vaccine the antibody response vaccinated individual vaccination Vaccination strategies vaccine-induced antibody response [DOI] 10.1080/22221751.2022.2030197 PMC 바로가기 [Article Type] Article
The long term vaccine-induced anti-SARS-CoV-2 immune response is impaired in quantity and quality under TNFα blockadeArticle Published on 2022-12-012022-11-15 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] Activation acute respiratory syndrome alteration analysed anti-SARS-CoV-2 anti-SARS-CoV-2 IgG anti-TNF-α appear Autoimmune Autoimmune diseases blockade bystander Cell changes in chronic inflammatory disease Cohort comparable Control coronavirus COVID-19 Decline drugs Effect Efficacy ELISA flow cytometry groups healthy humoral immune response IgG immune cell populations immune response immunoblot investigated less Live virus Necrosis Neutralization assay neutralize neutralizing antibody neutralizing capacity Older omicron Patient patients plasma Plasma cell recipient reduced response SARS-CoV-2 second vaccination significantly T cell subset titre TNF-α TNFα tumor necrosis factor inhibitors tumor necrosis factor-α vaccination vaccination. Vaccine variants of concern virus VoC was increased while [DOI] 10.1002/jmv.28063 PMC 바로가기
Omicron infections profile and vaccination status among 1881 liver transplant recipients: a multi-centre retrospective cohortArticle Published on 2022-12-012022-11-16 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, [키워드] acute respiratory syndrome adverse event adverse events Breakthrough infection China clinical manifestation Cohort collected concerning conducted coronavirus Coronavirus disease 2019 COVID-19 COVID-19 vaccination decrease Efficacy enrolled fatigue feature grade 3 higher risk inactivated Inactivated vaccine Infection infections liver liver dysfunction Liver transplantation Mild myalgia occurred omicron participant Patient patients postoperative protection rate. recipient retrospective cohort Retrospective study Safe safety profile SARS-CoV-2 Seven vaccination Vaccine variant viral shedding were infected whole-virion SARS-CoV-2 vaccine [DOI] 10.1080/22221751.2022.2136535 PMC 바로가기
SARS-CoV-2 vaccine booster in solid organ transplant recipients previously immunised with inactivated versus mRNA vaccines: A prospective cohort studyArticle Published on 2022-12-012022-10-06 Journal: Lancet Reg Health Am [Category] 진단, [키워드] age All participant anti-SARS-CoV-2 BNT162b2 BNT162b2 vaccine booster Care cohort study CoronaVac COVID-19 determine dose effective end point General population groups Heterologous heterologous vaccine homologous humoral immune response IFN-γ IgG antibody IL-2 inactivated kidney liver median Medicine more difficult mRNA mRNA vaccine neutralising antibody not differ of BNT162b2 outcome Patient priming proportion Prospective prospective cohort study recipient recipients Red SARS-CoV-2 SARS-CoV-2 vaccine School secondary secreting significantly significantly higher solid organ solid organ transplant SOT T-cell T-cell responses vaccination Vaccine vaccine immunogenicity. women [DOI] 10.1016/j.lana.2022.100371 PMC 바로가기 [Article Type] Article
Influenza and pneumococcal vaccination and COVID-19 in kidney transplant patientsResearch article Published on 2022-12-012022-10-05 Journal: Transplant immunology [Category] 변종, 진단, 치료제, [키워드] addition administration benefit Clinical course control group COVID COVID-19 COVID-19 infection disease Donor dysfunction examined follow-up time group Hospital stay Hospitalization increased the risk Influenza Influenza and pneumoccal vaccine intensive care kidney transplant kidney transplant recipient lack Logistic regression analysis median multivariate need for dialysis no significant difference observation outcome pandemic Patient pneumococcal positive recipient reduce Result risk of COVID-19 rRT-PCR test significantly higher the disease the patient vaccination vaccination rate Vaccine Vaccines with COVID-19 [DOI] 10.1016/j.trim.2022.101693 [Article Type] Research article
Neutralizing antibodies to SARS-CoV-2 variants of concern including Delta and Omicron in subjects receiving mRNA-1273, BNT162b2, and Ad26.COV2.S vaccinesArticle Published on 2022-12-012022-11-15 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] Ad26.COV2.S Ad26.COV2.S vaccine antibody B.1.1.529 B.1.1.7 B.1.351 B.1.617.2 Beta BNT162b2 BNT162b2 vaccine booster center contributed Control COVID-19 Delta dose Effectiveness elicited faster FIVE Gamma immunization moderate mRNA-1273 mRNA-based vaccine Mutation Neutralizing Neutralizing antibodies neutralizing antibody omicron P.1 postvaccination prevention Protein pseudovirus receiving recipient recommendation robust SARS-CoV-2 SARS-CoV-2 vaccine SARS-CoV-2 variant subject Support vaccination Vaccine vaccine efficacy variants of concern variants of concern (VOCs). VoC VOCs wild type [DOI] 10.1002/jmv.28032 PMC 바로가기
Real-world effectiveness of homologous and heterologous BNT162b2, CoronaVac, and AZD1222 booster vaccination against Delta and Omicron SARS-CoV-2 infectionDelta 및 Omicron SARS-CoV-2 감염에 대한 동종 및 이종 BNT162b2, CoronaVac 및 AZD1222 추가 백신 접종의 실제 효과Article Published on 2022-12-012022-09-11 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] AZD1222 BNT162b2 booster booster vaccination conducted CoronaVac country COVID-19 COVID-19 vaccines Delta demonstrated effective Effectiveness Evidence evidence of Heterologous heterologous booster homologous homologous booster Immune escape inactivated Malaysia National omicron percentage points recipient SARS-CoV-2 SARS-COV-2 infection the SARS-CoV-2 vaccination Vaccine vaccine effectiveness. Vaccines Viral viral variant [DOI] 10.1080/22221751.2022.2072773 PMC 바로가기 [Article Type] Article
A case-case study on the effect of primary and booster immunization with China-produced COVID-19 vaccines on prevention of pneumonia and viral load among vaccinated persons infected by Delta and Omicron variantsDelta 및 Omicron 변종에 감염된 백신 접종자의 폐렴 및 바이러스 부하 예방에 대한 중국산 COVID-19 백신의 1차 및 추가 접종 효과에 대한 사례 연구Article Published on 2022-12-012022-09-11 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, [키워드] administration age analysed association booster booster dose booster immunization calculate case study case-case study COVID-19 COVID-19 outbreak COVID-19 pneumonia COVID-19 vaccine Ct value Ct values Delta determine eligible evaluated immunization Infection infections less Logistic regression no difference no differences Odds ratio Odds ratios omicron pace Pneumonia real-world study. recipient reduced reduction SARS-CoV-2 viral load vaccination Vaccination Status variant Viral load [DOI] 10.1080/22221751.2022.2103455 PMC 바로가기 [Article Type] Article
Reduced humoral but stable cellular SARS-CoV-2-specific immunity in liver transplant recipients in the first year after COVID-19Article Published on 2022-11-022022-11-15 Journal: PLoS ONE [Category] SARS, 진단, 치료기술, [키워드] anti-Nucleocapsid IgG anti-SARS-CoV-2 anti-SARS-CoV-2 IgG antibody Antigen booster vaccination cellular cellular immunity Cohort Concentration convalescent COVID-19 detectable domain Endemic humoral IFN-γ IgG immune response Immunity Immunoglobulin Immunosuppressed Immunosuppression immunosuppressive individual liver Liver transplantation membrane nucleocapsid Prevalence protective immunity reactivity Receptor binding domain recipient remained retrieved robust SARS-CoV-2 significantly increased Spike protein stimulated T cell T cell response therapy vaccination [DOI] 10.1371/journal.pone.0276929 PMC 바로가기
Outcomes following SARS-CoV-2 infection in individuals with and without solid organ transplantation-A Danish nationwide cohort studyArticle Published on 2022-11-012022-11-16 Journal: American journal of transplantation : official jou [Category] COVID19(2023년), SARS, 변종, [키워드] 95%CI acute respiratory syndrome analysis assisted respiration calculate clinical research/practice Cohort cohort study comparable Contact coronavirus Cox regression death Effect General population hospital Hospitalization incidence rate increased risk increased the risk individual Infection infection and infectious agents - viral infection and infectious agents - viral: SARS-CoV-2/COVID-19 infectious agent Infectious disease lower risk Mortality omicron organ performed recipient reduce reduced risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccine SARS-CoV2 infection severe COVID-19 solid organ transplant solid organ transplantation solid organ transplantation. vaccination Vaccinations variant were used with COVID-19 [DOI] 10.1111/ajt.17142 PMC 바로가기